Title of article :
14β-Hydroxy-10-deacetylbaccatin III as a convenient, alternative substrate for the improved synthesis of methoxylated second-generation taxanes
Author/Authors :
Luciano Barboni، نويسنده , , Guido Giarlo، نويسنده , , Roberto Ballini، نويسنده , , Gabriele Fontana، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
This article describes a new, convenient, improved synthesis of the 2-debenzoyl-2-m-methoxybenzoyl-7-triethylsilyl-13-oxo-14β-hydroxybaccatin III 1,14-carbonate, the key intermediate in the synthesis of two new second-generation antitumor taxanes.
Keywords :
Second-generation taxanes , natural products , terpenoids , Antitumor agents , 14?-Hydroxy-10-deacetylbaccatin III
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
