Title of article :
Epibatidine isomers and analogues: Structure–activity relationships
Author/Authors :
Richard White، نويسنده , , John R. Malpass، نويسنده , , Sandeep Handa، نويسنده , , S. Richard Baker، نويسنده , , Lisa M. Broad، نويسنده , , Liz Folly، نويسنده , , Adrian Mogg، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
Binding affinities for a range of epibatidine isomers and analogues at the α4β2 and α3β4 nAChR subtypes are reported; compounds having similar N–N distances to epibatidine show similar, high potencies.
Keywords :
nicotinic receptor subtypes , nAChR affinity , Structure–activity relationships , Epibatidine isomers , Epibatidine analogues
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
