Title of article :
Synthesis of radiolabeled stilbene derivatives as new potential PET probes for aryl hydrocarbon receptor in cancers
Author/Authors :
Mingzhang Gao، نويسنده , , Min Wang، نويسنده , , Kathy D. Miller، نويسنده , , George W. Sledge Jr، نويسنده , , Gary D. Hutchins، نويسنده , , Qi-Huang Zheng، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
New carbon-11 and fluorine-18 labeled stilbene derivatives, cis-3,5-dimethoxy-4′-[11C]methoxystilbene (4′-[11C]8a), cis-3,4′,5-trimethoxy-3′-[11C]methoxystilbene (3′-[11C]8b), trans-3,5-dimethoxy-4′-[11C]methoxystilbene (4′-[11C]10a), trans-3,4′,5-trimethoxy-3′-[11C]methoxystilbene (3′-[11C]10b), cis-3,5-dimethoxy-4′-[18F]fluorostilbene (4′-[18F]12a), and trans-3,5-dimethoxy-4′-[18F]fluorostilbene (4′-[18F]13a), were designed and synthesized as potential PET probes for aryl hydrocarbon receptor (AhR) in cancers.
Keywords :
Aryl hydrocarbon receptor (AhR) , cancer , Carbon-11 , Stilbene derivatives , Fluorine-18 , Positron emission tomography (PET)
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
