Title of article :
Synthesis and antihyperlipidemic activity of novel glycosyl fructose derivatives
Author/Authors :
Pallavi Tiwari، نويسنده , , Anju Puri، نويسنده , , Ramesh Chander Kuhad and C. R. Babu ، نويسنده , , Geetika Bhatia، نويسنده , , Anup Kumar Misra، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
A series of novel di and trisaccharide derivatives containing d-fructose moiety at the reducing end have been synthesized and evaluated for their antihyperlipidemic activity in hyperlipidemic hamster model. Among 11 glycosyl fructose derivatives five compounds showed potent antihyperlipidemic activity either by enhancing high-density lipoprotein (HDL) cholesterol concentration and/or lowering triglyceride (TG) level.
Keywords :
D-fructose , Triglyceride , High-density cholesterol , Anti-hyperlipidemic , carbohydrate
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
