Title of article
Phosphate transfer from inositol pyrophosphates InsP5PP and InsP4(PP)2: A semi-empirical investigation
Author/Authors
Christine E. Hand، نويسنده , , John F. Honek، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
6
From page
183
To page
188
Abstract
A novel phosphate transfer process involving the non-enzymatic transfer of a phosphate group from inositol pyrophosphates to serine residues in proteins has been recently reported. Semi-empirical calculations at the PM3/SM5.2 level were undertaken to explore the effect of inositol pyrophosphate structure and overall charge on the thermodynamics of this phosphate transfer.
Keywords
Inositol pyrophosphate , IP7 , InsP5PP , IP8 , InsP4(PP)2 , Phosphate transfer , phosphorylation , Semi-empirical , PM3 , SM5.2
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797622
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