Title of article
Evolution of thiazolidine-based blockers of human Kv1.5 for the treatment of atrial arrhythmias
Author/Authors
Chris M. Jackson، نويسنده , , Benjamin Blass، نويسنده , , Keith Coburn، نويسنده , , Laurent Djandjighian، نويسنده , , Gina Fadayel، نويسنده , , Andrew J. Fluxe، نويسنده , , Steven J. Hodson، نويسنده , , John M. Janusz، نويسنده , , Michael Murawsky، نويسنده , , James M. Ridgeway، نويسنده , , Ronald E. White، نويسنده , , Shengde Wu، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
3
From page
282
To page
284
Abstract
Blockade of the Kv1.5 ion channel is a potentially atrial-selective avenue for the treatment of atrial fibrillation and atrial flutter. The development and biological evaluation of a series of thiazolidine-based blockers of Kv1.5 is described.
Keywords
atrial fibrillation , Potassium channel , Thiazolidine , Human Kv1.5 , Atrial-selective
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797642
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