Title of article
Synthesis of carbon-11 labeled sulfonanilide analogues as new potential PET agents for imaging of aromatase in breast cancer
Author/Authors
Min Wang، نويسنده , , Gabrielle Lacy، نويسنده , , Mingzhang Gao، نويسنده , , Kathy D. Miller، نويسنده , , George W. Sledge Jr، نويسنده , , Qi-Huang Zheng، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
5
From page
332
To page
336
Abstract
Aromatase is a particularly good target in the treatment of estrogen receptor positive breast cancer. Novel carbon-11 labeled sulfonanilide analogues, N-[11C]methyl-N-(2-alkyloxy-4-nitrophenyl)-methanesulfonamides ([11C]3a–f, alkyl = propyl, isopropyl, 1-ethyl-propyl, cyclopentyl, cyclohexyl, and cyclohexylethyl), were designed and synthesized as potential PET agents for imaging of aromatase in breast cancer.
Keywords
Carbon-11 , Sulfonanilide analogues , aromatase , breast cancer , Positron emission tomography (PET)
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797649
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