Title of article :
Synthesis and activity of Combretastatin A-4 analogues: 1,2,3-thiadiazoles as potent antitumor agents
Author/Authors :
Maojiang Wu، نويسنده , , Qiming Sun، نويسنده , , Chunhao Yang، نويسنده , , Dongdong Chen، نويسنده , , Jian Ding، نويسنده , , Yi Chen، نويسنده , , Liping Lin، نويسنده , , Yuyuan Xie، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
A series of 4,5-disubstitute-1,2,3-thiadiazole compounds were designed and synthesized as potent anticancer agents, some of them exhibited excellent in vitro and in vivo inhibitory activity.
Keywords :
antitumor , Combretastatin A-4 analogue , 1 , 2 , 3-Thiadiazoles , Tubulin
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters