Title of article
HeLa cells apoptosis induced by 1,7-dimethyl-1,4,7,10-tetraazacyclododecane
Author/Authors
Li Yang، نويسنده , , Feng Liang، نويسنده , , Min Liu، نويسنده , , Congyi Zheng، نويسنده , , Shuhui Wan، نويسنده , , Xiaoqin Xiong، نويسنده , , Xiaolian Zhang، نويسنده , , Zhi-Chao Shen ، نويسنده , , Xiang Zhou، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
5
From page
1818
To page
1822
Abstract
Preliminary pharmacological tests showed that 1,7-dimethyl-1,4,7,10-tetraazacyclododecane (DMC) had antitumor activity against HeLa and A549 cell lines in vitro. The HeLa cells apoptosis induced by DMC was examined by flow cytometric meter, and further confirmed by observing the morphological changes and DNA fragmentation. No observation of A549 cells induced apoptosis was observed by DMC.
Keywords
apoptosis , Antitumor activity , Macrocyclic polyamines
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797941
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