Title of article :
Synthesis and antibacterial activity of 4,5,6,7-tetrahydro-thieno[3,2-c]pyridine quinolones
Author/Authors :
Brijesh Kumar Srivastava، نويسنده , , Manish Solanki، نويسنده , , Bhupendra Mishra، نويسنده , , Rina Soni، نويسنده , , Sanjaya Jayadev، نويسنده , , Darshan Valani، نويسنده , , Mukul Jain، نويسنده , , Pankaj R. Patel، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
Synthesis and antibacterial activity of a number of substituted 4,5,6,7-tetrahydro-thieno[3,2-c]pyridine quinolones is reported. The antibacterial activities were evaluated in standard in vitro MIC assay method. Some of the compounds showed in vitro (MIC) antibacterial activity comparable to those of Gatifloxacin, Ciprofloxacin, and Sparfloxacin.
Keywords :
4 , 5 , 6 , 2-c]pyridine , Quinolone antibacterial agent , In vitro MIC assay , Linezolid resistant staphylococcus aureus , Gram-positive organism
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters