Title of article
Epoxygenase eicosanoids: Synthesis of tetrahydrofuran-diol metabolites and their vasoactivity
Author/Authors
J.R. Falck، نويسنده , , L. Manmohan Reddy، نويسنده , , Kihwan Byun، نويسنده , , William B. Campbell، نويسنده , , Xiu-Yu Yi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
5
From page
2634
To page
2638
Abstract
Eight members of a recently identified family of tetrahydrofuran-diols (THFDs), originating from epoxyeicosatrienoic acids (EETs), were prepared stereospecifically from d-(+)-glucose. The THFDs potently induced relaxation of pre-contracted bovine arteries.
Keywords
Eicosanoids , Epoxygenase , Tetrahydrofuran , Vasorelaxation , EETs
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
798096
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