مرکز منطقه ای اطلاع رساني علوم و فناوري - Evaluation of N-(phenylmethyl)-4-[5-(phenylmethyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-4-yl]benzamide inhibitors of Mycobacterium tuberculosis growth

Title of article :

Evaluation of N-(phenylmethyl)-4-[5-(phenylmethyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-4-yl]benzamide inhibitors of Mycobacterium tuberculosis growth

Author/Authors :

Michael D. Wall، نويسنده , , Michael Oshin، نويسنده , , Gavin A.C. Chung، نويسنده , , Tony Parkhouse، نويسنده , , Andrea Gore، نويسنده , , Esperanza Herreros، نويسنده , , Brian Cox، نويسنده , , Ken Duncan، نويسنده , , Brian Evans ، نويسنده , , Martin Everett، نويسنده , , Alfonso Mendoza، نويسنده ,

Issue Information :

روزنامه با شماره پیاپی سال 2007

Pages :

From page :

2740

To page :

2744

Abstract :

The biological evaluation of imidazopiperidines as FAS II inhibitors of Mycobacterium tuberculosis growth has been carried out with a view to assessment of potential as lead compounds for the development of a new TB drug. A summary of the hit evaluation and current challenges is described herein.

Keywords :

Mycobacterium tuberculosis , InhA , Imidazopiperidines

Journal title :

Bioorganic & Medicinal Chemistry Letters

Serial Year :

2007

Journal title :

Bioorganic & Medicinal Chemistry Letters

Record number :

798115

Link To Document :

https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=798115