Title of article
Formation of an enolate intermediate is required for the reaction catalyzed by 3-hydroxyacyl-CoA dehydrogenase
Author/Authors
Xiaojun Liu، نويسنده , , Guisheng Deng، نويسنده , , Xiusheng Chu، نويسنده , , Nan Li، نويسنده , , Long Wu، نويسنده , , Ding Li، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
4
From page
3187
To page
3190
Abstract
Fluorinated substrate analogs were synthesized and incubated with rat liver 3-hydroxyacyl-CoA dehydrogenase, which reveals that the formation of an enolate intermediate is required for the reaction catalyzed by the enzyme.
Keywords
Fatty acid oxidation , chronic stable angina , Enolate , 3-Hydroxyacyl-CoA dehydrogenase , Diabetes , Alzheimer’s disease
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
798202
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