Title of article :
Formation of an enolate intermediate is required for the reaction catalyzed by 3-hydroxyacyl-CoA dehydrogenase
Author/Authors :
Xiaojun Liu، نويسنده , , Guisheng Deng، نويسنده , , Xiusheng Chu، نويسنده , , Nan Li، نويسنده , , Long Wu، نويسنده , , Ding Li، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
Fluorinated substrate analogs were synthesized and incubated with rat liver 3-hydroxyacyl-CoA dehydrogenase, which reveals that the formation of an enolate intermediate is required for the reaction catalyzed by the enzyme.
Keywords :
Fatty acid oxidation , chronic stable angina , Enolate , 3-Hydroxyacyl-CoA dehydrogenase , Diabetes , Alzheimer’s disease
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
