Title of article
RXR–LXR heterodimer modulators for the potential treatment of dyslipidemia
Author/Authors
Bharat Lagu، نويسنده , , Barbara Pio، نويسنده , , Rimma Lebedev، نويسنده , , Maria Yang، نويسنده , , Patricia D. Pelton، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
7
From page
3497
To page
3503
Abstract
A number of RXR agonists were synthesized and screened in functional assays. The synthesis and the structure–activity relationship (SAR) within the series of compounds will be presented. Some in vivo data in rodent models for dyslipidemia and diabetes will also be presented.
Keywords
HDL , dyslipidemia , ABCA-1 , RXR , LDL , triglycerides , LXR , Diabetes
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
798261
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