Title of article :
RXR–LXR heterodimer modulators for the potential treatment of dyslipidemia
Author/Authors :
Bharat Lagu، نويسنده , , Barbara Pio، نويسنده , , Rimma Lebedev، نويسنده , , Maria Yang، نويسنده , , Patricia D. Pelton، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
A number of RXR agonists were synthesized and screened in functional assays. The synthesis and the structure–activity relationship (SAR) within the series of compounds will be presented. Some in vivo data in rodent models for dyslipidemia and diabetes will also be presented.
Keywords :
HDL , dyslipidemia , ABCA-1 , RXR , LDL , triglycerides , LXR , Diabetes
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
