Title of article :
Synthesis and antibacterial activity of 3-keto-6-O-carbamoyl-11,12-cyclic thiocarbamate erythromycin A derivatives
Author/Authors :
Zi-bin Zhu، نويسنده , , Brett A. Marinelli، نويسنده , , Darren Abbanat، نويسنده , , Barbara D. Foleno، نويسنده , , Karen Bush and Osnat Herzberg، نويسنده , , Mark J. Macielag، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
A series of 3-keto-6-O-carbamoyl-11,12-cyclic thiocarbamate erythromycin A derivatives has been synthesized. The best compounds in this series possess potent in vitro antibacterial activity against erythromycin-susceptible and erythromycin-resistant bacteria.
Keywords :
Erythromycin A , macrolide , Antibacterial , Ketolide
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
