Title of article
Synthesis of marine alkaloid: 8,9-Dihydrocoscinamide B and its analogues as Novel class of antileishmanial agents
Author/Authors
Leena Gupta، نويسنده , , Archna Talwar، نويسنده , , Nishi، نويسنده , , Shraddha Palne، نويسنده , , Suman Gupta، نويسنده , , Prem M.S. Chauhan، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
5
From page
4075
To page
4079
Abstract
A series of marine alkaloid 8,9-dihydrocoscinamide B, its analogues and indolylglyoxylamide derivatives have been synthesized and screened for their in vitro antileishmanial activity profile in promastigote and amastigote models. Compounds 7 and 10 have shown 99–100% inhibition against promastigotes and 97–98% inhibition against amastigotes at a concentration of 10 μg/ml.
Keywords
Indolylglyoxylamides , Dihydrocoscinamide B , Leishmania
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
798372
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