Title of article
Synthesis and evaluation of amphiphilic cationic quinine-derived for antibacterial activity against methicillin-resistant Staphylococcus aureu
Author/Authors
Jian Lv، نويسنده , , Yunbo Qian، نويسنده , , Tingting Liu، نويسنده , , Yongmei Wang، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
5
From page
4102
To page
4106
Abstract
Several representative amphiphilic cationic quinine-derived have been synthesized and evaluated against methicillin- resistant Staphylococcus aureus. This is the first reported antibacterial activity of this class of compounds. In vitro the minimal inhibitory concentration values of the best compound Q7 ranged from 0.4 to 1.6 μg/mL (MBC < 3.2 μg/mL).
Keywords
Amphiphilic cationic , Quinine-derived , Antibacterial activity , MRSA
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
798374
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