Title of article
Oxazolones as potent inhibitors of 11β-hydroxysteroid dehydrogenase type 1
Author/Authors
Lori Sutin، نويسنده , , S?ren Andersson، نويسنده , , Lars Bergquist، نويسنده , , Victor M. Castro، نويسنده , , Eva Danielsson، نويسنده , , Stephen James Steigrad، نويسنده , , Martin Henriksson، نويسنده , , Lars Johansson، نويسنده , , Christina Kaiser، نويسنده , , Katarina Flyrén، نويسنده , , Meredith Williams، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
4
From page
4837
To page
4840
Abstract
2,5,5-Trisubstituted oxazolones were identified as potent inhibitors of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). The synthesis, structure–activity relationship and metabolic stability of these compounds are presented.
Keywords
11?-HSD1 , Oxazolones , metabolic syndrome
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
798512
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