Title of article
A novel ketolide class: Synthesis and antibacterial activity of a lead compound
Author/Authors
Daniele Andreotti، نويسنده , , Ilaria Bientinesi، نويسنده , , Stefano Biondi، نويسنده , , Daniele Donati، نويسنده , , Isabelle Erbetti، نويسنده , , Sergio Lociuro، نويسنده , , Carla Marchioro، نويسنده , , Alfonso Pozzan، نويسنده , , Emiliangelo Ratti، نويسنده , , Silvia Terreni، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
5
From page
5265
To page
5269
Abstract
Synthesis and antibacterial activity of a new class of ketolide antibiotics, exemplified by the prototype GW680788X (1), are described. The structure of (1) has been elucidated by spectroscopic analysis. The good antibacterial activity shown by (1) in comparison with clarithromycin prompted us to consider this compound as a lead molecule for further exploration.
Keywords
Macrolides , ketolides , Antibacterial , GW680788X
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
798595
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