Title of article
Synthesis and antibacterial activity of some novel chiral fluorophoric biscyclic macrocycles
Author/Authors
Perumal Rajakumar، نويسنده , , Subramaniyan Selvam، نويسنده , , Vellaisamy Shanmugaiah، نويسنده , , Narayanasamy Mathivanan، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
4
From page
5270
To page
5273
Abstract
Synthesis of chiral permanent fluorophoric biscyclic macrocycles incorporating anthraquinone and (S)-BINOL core is described. Interestingly, the biscyclic macrocycle 1 exhibited remarkable antibacterial activity against most of the pathogenic bacteria in the tested concentrations as compared to the other three compounds 2, 14 and 17 as well as the test control, tetracycline. Further biscyclophanes 1 and 2 exhibited permanent fluorescence sensing property even under highly acidic conditions.
Keywords
Antibacterial activity , Chiral fluorophoric biscyclic macrocycles
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
798596
Link To Document