Title of article
Synthesis of the A,B-ring-truncated OSW saponin analogs and their antitumor activities
Author/Authors
Wenjie Peng، نويسنده , , Pingping Tang، نويسنده , , Xiaoyi Hu، نويسنده , , Jun O. Liu، نويسنده , , Biao Yu، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
4
From page
5506
To page
5509
Abstract
The A,B-ring-truncated OSW saponin analogs (1, 18a, and 18b) were synthesized. These greatly simplified trans-hydrindane disaccharides retained considerable inhibitory activity against the growth of HeLa and Jurkat T cells (IC50 = 0.8–21.1 μM).
Keywords
glycosides , OSW saponins , synthesis , Antitumor activity , trans-hydrindane
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
798641
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