Title of article :
Synthesis of the A,B-ring-truncated OSW saponin analogs and their antitumor activities
Author/Authors :
Wenjie Peng، نويسنده , , Pingping Tang، نويسنده , , Xiaoyi Hu، نويسنده , , Jun O. Liu، نويسنده , , Biao Yu، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
The A,B-ring-truncated OSW saponin analogs (1, 18a, and 18b) were synthesized. These greatly simplified trans-hydrindane disaccharides retained considerable inhibitory activity against the growth of HeLa and Jurkat T cells (IC50 = 0.8–21.1 μM).
Keywords :
glycosides , OSW saponins , synthesis , Antitumor activity , trans-hydrindane
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
