Title of article :
Synthesis of 2,3-diaryl-1,3-thiazolidine-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors
Author/Authors :
Afshin Zarghi، نويسنده , , Leila Najafnia، نويسنده , , Bahram Daraee، نويسنده , , Orkideh G. Dadrass، نويسنده , , Mehdi Hedayati، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
A group of 2,3-diaryl-1,3-thiazolidine-4-ones, possessing a methylsulfonyl pharmacophore, were synthesized and their biological activities were evaluated for cyclooxygenase-2 (COX-2) inhibitory activity.
Keywords :
1 , 3-Thiazolidine-4-ones , COX-2 inhibition , SAR
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters