Title of article
Cytotoxic and apoptotic activities of novel amino analogues of boswellic acids
Author/Authors
Bhahwal A. Shah، نويسنده , , Ajay Kumar، نويسنده , , Pankaj Gupta، نويسنده , , Madhunika Sharma، نويسنده , , Vijay K. Sethi، نويسنده , , Ajit K. Saxena، نويسنده , , Jaswant Singh، نويسنده , , Ghulam N. Qazi، نويسنده , , Subhash C. Taneja، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
6
From page
6411
To page
6416
Abstract
4-Amino analogues prepared from β-boswellic acid and 11-keto-β-boswellic acid, wherein the carboxyl group in ursane nucleus was replaced by an amino function via Curtius reaction, displayed improved cytotoxicity than the parent molecules. The same molecules also exhibited apoptotic activity by inducing DNA fragmentation.
Keywords
11-Keto-?-boswellic acid , Amino analogues , Epimers , cytotoxicity , DNA fragmentation , ?-Boswellic acid
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
798814
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