Title of article
Synthesis and antitumor activity of amine analogs of irofulven
Author/Authors
Trevor C. McMorris، نويسنده , , Ramesh Chimmani، نويسنده , , Mahender Gurram، نويسنده , , Michael D. Staake، نويسنده , , Michael J. Kelner، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
3
From page
6770
To page
6772
Abstract
Acylfulvenes, a class of semisynthetic analogs of Illudin S, show high toxicity toward prostate cancer cells. Here we probe the effect of changes in hydrophilic character of the analogs.
Keywords
Irofulven , Analogs synthesis , Staudinger ligation , Antitumor activity , reductive amination
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2007
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
798883
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