Title of article
Design, synthesis and antimalarial activity of benzene and isoquinoline sulfonamide derivatives
Author/Authors
Maloy Kumar Parai، نويسنده , , Gautam Panda، نويسنده , , Kumkum Srivastava، نويسنده , , Sunil Kumar Puri، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
6
From page
776
To page
781
Abstract
A new series of benzene and isoquinoline sulfonamide derivatives were synthesized by nucleophilic displacement reaction on benzene and isoquinoline sulfonyl chlorides by substituted amines (primary and secondary). The title compounds were evaluated for antimalarial activity against Plasmodium falciparum in vitro and showed MIC in the range of 2–50 μg/mL.
Keywords
Benzene and isoquinoline sulfonamides , antimalarial activity
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
799058
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