Title of article
A novel bicyclic hexapeptide, RA-XVIII, from Rubia cordifolia: Structure, semi-synthesis, and cytotoxicity
Author/Authors
Ji-Ean Lee، نويسنده , , Yukio Hitotsuyanagi، نويسنده , , Ik-Hwi Kim، نويسنده , , Tomoyo Hasuda، نويسنده , , Koichi Takeya، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
4
From page
808
To page
811
Abstract
A new bicyclic peptide of RA-series, RA-XVIII (3), was isolated from the roots of Rubia cordifolia L. Its structure was established to be a hydroxylated derivative of RA-VII by the semi-synthesis of 3 from deoxybouvardin, and its cytotoxicity against P-388 cells was 0.012 μg/mL.
Keywords
RA-XVIII , cytotoxicity , synthesis , Deoxybouvardin , Rubia cordifolia
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
799064
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