Author/Authors :
Stephen Hanessian، نويسنده , , Sébastien Guesné، نويسنده , , Ludivine Riber، نويسنده , , Julien Marin، نويسنده , , Alain Benoist، نويسنده , , Philippe Mennecier، نويسنده , , Alain Rupin، نويسنده , , Tony J. Verbeuren، نويسنده , , Guillaume De Nanteuil، نويسنده ,
Abstract :
A series of urea analogues related to SA6817 and a GSK phosphonic acid with reported ACE inhibitory activity were prepared and tested for dual ACE and ECE activities. Although excellent ACE and NEP inhibition was achieved, only modest ECE inhibition was observed with one analogue.
