Title of article
Indole- and indolizine-glyoxylamides displaying cytotoxicity against multidrug resistant cancer cell lines
Author/Authors
David A. James، نويسنده , , Keizo Koya، نويسنده , , Hao Li، نويسنده , , Guiqing Liang، نويسنده , , Zhiqiang Xia، نويسنده , , Weiwen Ying، نويسنده , , Yaming Wu، نويسنده , , Lijun Sun، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
4
From page
1784
To page
1787
Abstract
We report herein the SAR studies of a series of indole- and indolizine-glyoxylamides that demonstrate substantial in vitro anti-proliferative activities against cancer cell lines, including multidrug resistance (MDR) phenotypes. The in vitro cytotoxic effects have been demonstrated across a wide array of tumor types of various origins (e.g., breast, colon, uterine).
Keywords
Indolizine , Multidrug , Resistant , cancer , Cytotoxic , Glyoxylamide , indole
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
799246
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