Title of article :
Synthesis and bioevaluation of 22-hydroxyacuminatine analogs
Author/Authors :
François Grillet، نويسنده , , Barbora Baumlov?، نويسنده , , Grégoire Prévost، نويسنده , , Jean-François Constant، نويسنده , , Sophie Chaumeron، نويسنده , , Dennis C.H. Bigg، نويسنده , , Andrew E. Greene، نويسنده , , Alice Kanazawa، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2008
Pages :
4
From page :
2143
To page :
2146
Abstract :
A series of 22-hydroxyacuminatine analogs was prepared by using different Friedländer condensations. Several of the new compounds were tested for antiproliferative activity on cancer cell lines and for topoisomerase I inhibitory activity.
Keywords :
topoisomerase I , cytotoxicity , synthesis , camptothecin , 22-Hydroxyacuminatine analogs
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2008
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
799313
Link To Document :
بازگشت