Title of article
Synthesis and bioevaluation of 22-hydroxyacuminatine analogs
Author/Authors
François Grillet، نويسنده , , Barbora Baumlov?، نويسنده , , Grégoire Prévost، نويسنده , , Jean-François Constant، نويسنده , , Sophie Chaumeron، نويسنده , , Dennis C.H. Bigg، نويسنده , , Andrew E. Greene، نويسنده , , Alice Kanazawa، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
4
From page
2143
To page
2146
Abstract
A series of 22-hydroxyacuminatine analogs was prepared by using different Friedländer condensations. Several of the new compounds were tested for antiproliferative activity on cancer cell lines and for topoisomerase I inhibitory activity.
Keywords
topoisomerase I , cytotoxicity , synthesis , camptothecin , 22-Hydroxyacuminatine analogs
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
799313
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