Title of article
Tritium radiolabelling of PB28, a potent sigma-2 receptor ligand: pharmacokinetic and pharmacodynamic characterization
Author/Authors
Nicola Antonio Colabufo، نويسنده , , Carmen Abate، نويسنده , , Marialessandra Contino، نويسنده , , Carmela Inglese، نويسنده , , Savina Ferorelli، نويسنده , , Francesco Berardi، نويسنده , , Roberto Perrone، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
5
From page
2183
To page
2187
Abstract
A potent sigma-2 receptor ligand, known as PB28, was tritium radiolabelled and biologically evaluated. The results showed that [3H]PB28 and the corresponding unlabelled PB28 had superimposed pharmacodynamic properties. This radioligand appears as a potential candidate for receptor binding and in living cells assays.
Keywords
Sigma-2 receptors
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
799321
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