Title of article
Increasing permeability of phospholipid bilayer membranes to alanine with synthetic α-aminophosphonate carriers
Author/Authors
Delia C. Danila، نويسنده , , Xinyan Wang، نويسنده , , Heather Hubble، نويسنده , , Igor S. Antipin، نويسنده , , Eugene Pinkhassik، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
4
From page
2320
To page
2323
Abstract
A series of aminophosphonates was synthesized, and their ability to carry alanine, a model hydrophilic molecule, across phospholipid bilayer membranes was evaluated. Aminophosphonates facilitate the membrane transport at moderate rates, which make them a suitable platform for the design of carriers for continuous drug release devices.
Keywords
carriers , drug delivery , bilayers , aminophosphonates , liposomes , amino acids
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
799349
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