Title of article :
Discovery of 2-amino-6-carboxamidobenzothiazoles as potent Lck inhibitors
Author/Authors :
Shenlin Huang، نويسنده , , Zuosheng Liu، نويسنده , , Shin-Shay Tian، نويسنده , , Mark Sandberg، نويسنده , , Tracy A. Spalding، نويسنده , , Russell Romeo، نويسنده , , Maya Iskandar، نويسنده , , Zhiliang Wang، نويسنده , , Donald Karanewsky، نويسنده , , Yun He، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2008
Pages :
5
From page :
2324
To page :
2328
Abstract :
A novel series of 2-amino-6-carboxamidobenzothiazole was discovered to have potent Lck inhibitory properties. A highly efficient chemistry was developed. Also described are the detailed SAR study and the BaF3 cell line profiling for this series.
Keywords :
Lck inhibitor , 2-Amino-6-carboxamidobenzothiazole
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2008
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
799350
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=799350
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