Title of article
A novel pyrene-guanidiniocarbonyl-pyrrole cation efficiently differentiates between ds-DNA and ds-RNA by two independent, sensitive spectroscopic methods
Author/Authors
Laura Hernandez-Folgado، نويسنده , , Carsten Schmuck، نويسنده , , Sanja Tomi?، نويسنده , , Ivo Piantanida، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
5
From page
2977
To page
2981
Abstract
At micromolar concentrations and equimolar conditions in respect to basepairs, a novel pyrene-guanidiniocarbonyl-pyrrole cation 1 exhibited a strong ICD signal at about λ = 300 nm specifically upon the interaction with ds-DNA, while under the same conditions a new fluorescence maximum at λ = 480 nm appeared exclusively upon the addition of ds-RNA.
Keywords
pyrene , ds-RNA , Guanidinium , ds-DNA , pyrrole
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
799485
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