Title of article :
Enhanced anti-influenza A virus activity of (−)-epigallocatechin-3-O-gallate fatty acid monoester derivatives: Effect of alkyl chain length
Author/Authors :
Shuichi Mori، نويسنده , , Shinya Miyake، نويسنده , , Takayoshi Kobe، نويسنده , , Takaaki Nakaya، نويسنده , , Stephen D. Fuller، نويسنده , , Nobuo Kato، نويسنده , , Kunihiro Kaihatsu، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2008
Abstract :
A series of fatty acid monoester derivatives of (−)-epigallocatechin-3-O-gallate (EGCG) were prepared by one-pot lipase-catalyzed transesterification. The introduction of long alkyl chains enhanced anti-influenza A/PR8/34 (H1N1) virus activity 24-fold relative to native EGCG.
Keywords :
Epigallocatechin gallate , Lipase-catalyzed esterification , Antivirus agent , influenza virus
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
