Title of article :
Metal-free artificial nucleases based on simple oxime and hydroxylamine scaffolds
Author/Authors :
Luciano Fernandes، نويسنده , , Franciele L. Fischer، نويسنده , , Carolina W. Ribeiro، نويسنده , , Gustavo P. Silveira، نويسنده , , Marcus M. S?، نويسنده , , Faruk Nome، نويسنده , , Hern?n Terenzi، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2008
Abstract :
Hydrolysis of DNA is of increasing importance in biotechnology and medicine. In this Letter, we present the DNA-cleavage potential of metal-free hydroxylamines and oximes as new members of nucleic acid cleavage agents.
Keywords :
Metal-free nuclease , oximes , Hydroxylamines , DNA cleavage
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
