Title of article :
Structure–activity relationship studies of the chromosome segregation inhibitor, Incentrom A
Author/Authors :
Hee-Yoon Lee، نويسنده , , Yongsik Jung، نويسنده , , Wonyeob Kim، نويسنده , , Jin Hee Kim، نويسنده , , Min Soo Suh، نويسنده , , Seung Koo Shin، نويسنده , , Hye-Joo Yoon، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2008
Abstract :
A series of Incentrom A analogs that inhibit the chromosome segregation process in yeast were synthesized and tested for their effects on chromosome stability and cell proliferation. Pharmacophore and structure–activity relationship of Incentrom A for the anti-yeast activity were established.
Keywords :
Incentrom A , Pharmacophore , Inhibition , Chromosome segregation , structure–activity relationship , Yeast
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
