Title of article
Pyridyl and thiazolyl bisamide CSF-1R inhibitors for the treatment of cancer
Author/Authors
David A. Scott، نويسنده , , Brian M. Aquila، نويسنده , , Geraldine A. Bebernitz، نويسنده , , Donald J. Cook، نويسنده , , Les A. Dakin، نويسنده , , Tracy L. Deegan، نويسنده , , Maureen M. Hattersley، نويسنده , , Stephanos Ioannidis، نويسنده , , Paul D. Lyne، نويسنده , , Charles A. Omer، نويسنده , , Minwei Ye، نويسنده , , Xiaolan Zheng، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
4
From page
4794
To page
4797
Abstract
The bisamide class of kinase inhibitors was identified as being active against CSF-1R. The synthesis and SAR of pyridyl and thiazolyl bisamides are reported, along with the pharmacokinetic properties and in vivo activity of selected examples.
Keywords
Kinase inhibitors , Bisamide , Thiazole , CSF-1R
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
799889
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