Title of article
Design, synthesis, and antibacterial activities of novel 3,6-bicyclolide oximes: Length optimization and zero carbon linker oximes
Author/Authors
Datong Tang، نويسنده , , Yonghua Gai، نويسنده , , Alexander Polemeropoulos، نويسنده , , Zhigang Chen، نويسنده , , Zhe Wang، نويسنده , , Yat Sun Or، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
5
From page
5078
To page
5082
Abstract
We designed and synthesized a series of novel 3,6-bicyclolide oximes, possessing linkers of varying lengths to the secondary binding site. The E isomers exhibited excellent antibacterial profiles against a broad spectrum of resistant pathogens.
Keywords
Antibacterial , Bicyclolide , oxime , MIC
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
799953
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