Title of article :
Design, synthesis, and antibacterial activities of novel 3,6-bicyclolide oximes: Length optimization and zero carbon linker oximes
Author/Authors :
Datong Tang، نويسنده , , Yonghua Gai، نويسنده , , Alexander Polemeropoulos، نويسنده , , Zhigang Chen، نويسنده , , Zhe Wang، نويسنده , , Yat Sun Or، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2008
Abstract :
We designed and synthesized a series of novel 3,6-bicyclolide oximes, possessing linkers of varying lengths to the secondary binding site. The E isomers exhibited excellent antibacterial profiles against a broad spectrum of resistant pathogens.
Keywords :
Antibacterial , Bicyclolide , oxime , MIC
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
