Title of article
Synthesis and anti-CVB 3 evaluation of substituted 5-nitro-2-phenoxybenzonitriles
Author/Authors
Gerhard Pürstinger، نويسنده , , Armando M. De Palma، نويسنده , , Günther Zimmerhofer، نويسنده , , Simone Huber، نويسنده , , Sophie Ladurner، نويسنده , , Johan Neyts، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
3
From page
5123
To page
5125
Abstract
The synthesis and SAR of a series of 60 substituted 2-phenoxy-5-nitrobenzonitriles (analogues of MDL-860) as inhibitors of enterovirus replication (in particular of coxsackievirus B3 (CVB 3)) are reported. Several of the analogues inhibited CVB 3 and other enteroviruses at low-micromolar concentrations.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
799963
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