Title of article :
Synthesis and free radical scavenging activity of some new spiropyranocoumarins
Author/Authors :
Vassiliki Panteleon، نويسنده , , Ioannis K. Kostakis، نويسنده , , Panagiotis Marakos، نويسنده , , Nicole Pouli، نويسنده , , Ioanna Andreadou، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2008
Abstract :
A series of novel spiro-substituted 4-hydroxypyranocoumarins and their corresponding dihydropyrano cis-diols has been synthesized. Among them the spiroadamantylpyranocoumarin and the diols can interact with the stable free radical 1,1-diphenyl-2-picrylhydrazyl and scavenge superoxide anions generated in the xanthine–xanthine oxidase system.
Keywords :
coumarins , Spiropyranocoumarins , antioxidant activity , Radical scavenging effect , 1 , 1-Diphenyl-2-picrylhydrazyl (DPPH)
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters