Author/Authors :
Yanzhi Zhang، نويسنده , , Xicheng Sun، نويسنده , , Douglas J. Zeckner، نويسنده , , Roberta K. Sachs، نويسنده , , William L. Current، نويسنده , , Shu-Hui Chen، نويسنده ,
Abstract :
During the course of a structure–activity relationship (SAR) study on novel depsinonapeptide pseudomycin B, we synthesized a total of 12 8-amidopseudomycin analogues via standard two-step sequence from either ZPSB 2 or AllocPSB 3. A number of these amides exhibited good in vitro antifungal activities.
