• Title of article

    Anthraquinone-peptides as inhibitors of AP-1 transcription factor

  • Author/Authors

    Taeeba Ijaz، نويسنده , , Phoung Tran، نويسنده , , Ketan C. Ruparelia، نويسنده , , Paul H. Teesdale-Spittle، نويسنده , , Samantha Orr، نويسنده , , Laurence H. Patterson، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2001
  • Pages
    3
  • From page
    351
  • To page
    353
  • Abstract
    Peptide-1-[N-{2-succinamidylethyl}amino]anthraquinones containing five–seven amino acid residues including the KCR motif important in AP-1 protein binding to DNA have been synthesised as potential transcription factor inhibitors. These anthraquinone-peptides showed DNA intercalative binding and inhibition of AP-1 protein binding to its DNA consensus sequence.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2001
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    800344