Title of article
Bicyclic nucleoside inhibitors of Varicella-Zoster virus (VZV): the effect of terminal unsaturation in the side chain
Author/Authors
Sheila Srinivasan، نويسنده , , Christopher McGuigan، نويسنده , , Graciela Andrei، نويسنده , , Robert Snoeck، نويسنده , , Erik De Clercq، نويسنده , , Jan Balzarini، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
3
From page
391
To page
393
Abstract
Novel bicyclic nucleoside analogues bearing long alkyl side chains are prepared and tested as inhibitors of VZV. In particular, analogues with terminal unsaturation in the side chain are reported. Whilst terminal alkenyl derivatives are potent antivirals, the corresponding terminal alkynyls are poorly active.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
800354
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