Title of article :
Modified synthesis and antiangiogenic activity of linomide
Author/Authors :
Saeed R. Khan، نويسنده , , Annastasiah Mhaka، نويسنده , , Roberto Pili، نويسنده , , John T. Isaacs، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2001
Abstract :
A modified procedure for the synthesis of Linomide is described. The synthesized drug was characterized and assessed for its in vivo antiangiogenic activity. In a murine angiogenesis assay Linomide treatment inhibited new blood vessel formation as documented by reduced microvessel area and blood volume.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
