Title of article
Pimarane cyclooxygenase 2 (COX-2) inhibitor and its structure–activity relationship
Author/Authors
Young-Ger Suh، نويسنده , , Young-Ho Kim، نويسنده , , Mi-Hyoun Park، نويسنده , , Young-Hoon Choi، نويسنده , , Hye-Kyung Lee، نويسنده , , Ju-Yeon Moon، نويسنده , , Kyung-Hoon Min، نويسنده , , Dong-Yun Shin، نويسنده , , Jae-Kyung Jung، نويسنده , , Ok-Hui Park، نويسنده , , Ra-Ok Jeon، نويسنده , , Hyung-Sup Park، نويسنده , , Soon-Ah Kang، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
4
From page
559
To page
562
Abstract
The structure–activity relationship and molecular modelings of a novel pimarane COX-2 inhibitor are reported. Particularly, a series of linker extended analogues designed on the basis of these studies exhibited significantly enhanced COX-2 inhibitory activities and selectivities.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
800395
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