Title of article
Resultants in genetic linkage analysis
Author/Authors
Ingileif B. Hallgr?msd?ttir، نويسنده , , Shmuel Onn and Bernd Sturmfels، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
13
From page
125
To page
137
Abstract
Statistical models for genetic linkage analysis of k locus diseases are k-dimensional subvarieties of a (3k−1)-dimensional probability simplex. We determine the algebraic invariants of these models with general characteristics for k=1; in particular we recover, and generalize, the Hardy–Weinberg curve. For k=2, the algebraic invariants are presented as determinants of 32×32-matrices of linear forms in nine unknowns, a suitable format for computations with numerical data.
Keywords
Genetic linkage analysis , Resultants , Complex disease , Algebraic statistics
Journal title
Journal of Symbolic Computation
Serial Year
2006
Journal title
Journal of Symbolic Computation
Record number
805902
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