Author/Authors :
David L. Earnest، نويسنده , , Richard E. Sampliner، نويسنده , , Denise J. Roe، نويسنده , , Barbara van Leeuwen، نويسنده , , Jose Guillen، نويسنده , , Mary Reid، نويسنده , , Maria Elena Martinez، نويسنده , , James R. Marshall، نويسنده , , David S. Alberts، نويسنده ,
Abstract :
A double-blind, placebo-controlled Phase III cancer prevention trial in subjects with previous resection of adenomatous colon polyps is nearing completion. The study’s primary objective is to evaluate the effects of daily dietary supplementation with large (13.5 g/day) versus small (2.0 g/day) doses of wheat bran fiber for 3 years. A summary of the study design and a progress report are presented.