Advanced oxidation protein products (AOPP) and high-sensitive C-reactive protein (hs-CRP) in an “atheroma-free model”: Downʹs syndrome

Murdoch et al. in 1977 called Down syndrome an “atheroma-free model.” In this preliminary study, we investigated advanced oxidation protein products (AOPP) and high-sensitive C-reactive protein (hs-CRP) in 47 age-matched Down syndrome patients and 20 age-matched healthy controls. In these healthy patients, we detected no new biochemical risk factors for atherosclerosis, such as AOPP and hs-CRP, so risks are probably considerably lower.