Coronary stent implantation may seal the inflammatory response in patients with acute coronary syndromes

The change in CD40L levels before and 24 h coronary stenting was compared in patients presenting with acute coronary syndromes and for elective angioplasty. Baseline CD40L levels were lower in stable subjects, whereas unstable patients had a significant decrease of CD40L after stenting. This might suggest that coronary stenting, despite of being a local therapy, can help to seal a systemic inflammatory response in acute coronary syndromes.