Conformational study of the proline rich peptide from bovine neurohypophysis secretory granules

The spatial organization and conformational properties of the Proline Rich Peptide (PRP) from bovine neurohypophysis secretory granules have been established by the methods of molecular mechanics and molecular dynamics simulations in water solution. Conformational studies showed the peptide with limited conformational flexibility. Two b-type III turns are observed in PRP spatial organization. q 2003 Elsevier B.V. All rights reserved.